Publication, Patent etc.

Research Paper

R. U. Kadam, A. Chavan and N. Roy (2007) Pharmacophoric features of Pseudomonas aeruginosa deacetylase LpxC inhibitors: An electronic and structural analysis. Bioorg Med Chem Lett. 17:861-868.

S. Deswal and N. Roy (2006) A novel range based QSAR study of human neuropeptide Y (NPY ) Y5 receptor inhibitors. Eur. J. Med. Chem. Nov 1; [Epub ahead of print]

R. U. Kadam, V. M. Kiran and N.Roy (2006) Comparative protein modeling and surface analysis of Leishmania sirtuin: A potential target for antileishmanial drug discovery. Bioorg. Med. Chem. Lett. 16:6013-6018.

R.U. Kadam and N.Roy (2006) Cluster analysis and 2-Dimensional Quantitative Structure Activity Relationship (2D-QSAR) of Pseudomonas aeruginosa Deacetylase LpxC inhibitors. Bioorg. Med. Chem. Lett. 16:5136-5143

S. Deswal and N. Roy (2006) Quantitative structure activity relationship studies of aryl heterocycle-based thrombin inhibitors. Eur. J. Med. Chem. 41:1339-1346.

S. Deswal and N. Roy (2006) Quantitative Structure Activity Relationship of Benzoxazinone Derivatives as Neuropeptide Y Y5 Receptor Antagonists. Eur. J. Med. Chem. 41:552-557

I. Bala, V. Bhardwaj, S. Hariharan, S.V. Karade, N. Roy and M. N. V. Ravi Kumar (2006) Sustained release nanopaticulate formulation containing antioxidant-ellagic acid as potential prophylaxis system for oral administration. Journal of Drug Targeting 14:27-34

C.B. Tripathy and N. Roy (2006) GSTM1 genotype and risk towards Head and Neck cancer in Asians and Caucasians: A Meta-analysis study. Head and Neck 28: 217-224

S.V. Kharade, N. Mittal, S.P. Das, P. Sinha and N. Roy (2005) Mrg19 Depletion Increases S. cerevisiae Lifespan by Augmenting ROS Defence. FEBS Letters 579: 6809-6813

S. Agarwal, S. Sharma, V. Agarwal and N. Roy (2005) Caloric Restriction Augments ROS Defense in S. cerevisiae, by a Sir2p Independent Mechanism. Free Radical Research 39:55-62

A. Ray, R.E. Hector, N. Roy, J.H. Song, K.L.Berkner, K.W. Runge (2003) Sir3p phosphorylation by the Slt2p pathway effects redistribution of silencing function and shortened lifespan. Nature Genetics 33: 522-526

Patent

Jain, R.; Monga, V.; Kaur, N.; Sharma, S. S.; Kumar, S.; Roy, N.; Majumdar, J.; Agarwal, S.; Pawar, C.; Kadam, R. U.; Chavan, A. CNS effective thyrotropin releasing hormone analogs. WTO Indian Patent Application No. 2065/DEL/2006 filing date Sep 2006

N. Roy and S. Pahwa "Novel histidinol dehydrogenase from Geotrichum candidum". Indian patent application number 348/DEL/2006 filing date Feb 2006.

N. Roy, V. Agrawal, and U. C. Banerjee, "Recombinant AnigAP from Aspergillus niger van Teighem and use of thereof". Indian patent application number 20/DEL/2006 filing date Jan 2006.

A. K Bansal, N. Trasi, A. M. Kashal, U. C. Banerjee, N. Roy "A process for preparing a storage stable freezedried phytase composition". Indian patent application number 2557/DEL/2004 filing date Dec 2004

Sequence and Strain

V. Agrawal, U. C. Banerjee and N. Roy (2007) Aspergillus niger van Teigham MTCC F0101 pH 2.5 acid phosphatase (aph) gene cDNA. Direct submission GenBank Accession no EF177460 Release date Jan 1 2008

A. V. Shivange, V. Agrawal and N. Roy (2007) Entamoeba histolytica HM-1:IMSS Sir2 family transcriptional regulator, genomic sequence. Direct submission GenBank Accession no EF202834 Release date Feb 1 2008

V. Agrawal, U. C. Banerjee and N. Roy (2006) Aspergillus niger van Teigham MTCC F0101 pH 2.5 acid phosphatase (aph) gene with alpha factor secretory signal for extracellular secretion in Saccharomyces cerevisiae. Direct submission GenBank Accession no DQ787156 Release date Jun 30, 2007

S. Pahwa and N. Roy (2006) Galactomyces geotrichum HIS4 (HIS4) gene, complete cds.. Direct submission GenBank Accession No DQ463160 Release date Dec 31 2006

N. Roy and S. Pahwa "Novel histidinol dehydrogenase from Geotrichum candidum". Patented strain Accession Number MTCC 5265 Deposited at International Depositary Authority (IDA), Microbial Type Culture Collection and Gene Bank (MTCC), IMTECH (CSIR), Sector-39A, Chandigarh - 160 036

S. Pahwa and N. Roy (2005) Geotrichum candidum Histidinol dehydrogenase gene cds. Direct submission GenBank Accession No DQ297763 Release date Dec 31 2006

V. Agrawal, U. C. Banerjee and N. Roy (2005) Aspergillus niger van Teighem MTCC F0101 pH 2.5 acid phosphatase (aph) gene. complete cds Direct submission GenBank Accession No DQ297678 Release date Dec 31 2006

Database

GenMAPP database for fission yeast. A custom Gene Database and MAPP Archives for Schizosaccharomyces pombe have been created through collaboration with J. David Gladstone Institutes, at the University of California, San Francisco.
GenMAPP (Gene Map Annotator and Pathway Profiler; http://www.genmapp.org) is a free stand-alone computer program, designed and developed by the Conklin group; it assists in viewing and analyzing omics data in the context of biological pathways as well as the Gene Ontology (GO).

Download the database and MAPPs from http://www.databases.niper.ac.in/Pombe/

LishBase; A database of 7000 L. major genes for in house reserch.

DiaBase; A demo database of 65 diabetes genes, in collaboration with BrainWave Biosolutions, Chennai

Review and book chapter

P. Garg, J. Verma and N. Roy (2006) In Silico Modeling for Blood Brain Barrier Permeability Predictions in Preclinical Biopharmaceutics - in situ, in vitro, and in silico tools for drug absorption studies ed Carsten Ehrhardt and Kwang-Jin (in press)

S. Deswal and N. Roy (2006) Computational analysis of microarray data CRIPS 7: 2-7

S. Deswal, R. U. Kadam and N. Roy (2005) Homology Modeling in Target Identification and Validation. CRIPS 6: 7-11

V. M. Kiran and N. Roy Text Mining: The New Frontier in Medical Informatics. CRIPS 5:9-11

S. Agarwal and N. Roy (2003) Therapeutic protein production; a brief sketch. Future Drug Discovery, (WMRC) pp 79-82

N. Roy (2002) Proteomics and Future Drug Discovery. Future Drug Discovery, (WMRC) pp 100-103

S. Agarwal, A. Chaturvedi and N. Roy (2002) Pharmacogenomics: The Concepts Behind Personalized Medicine CRIPS 3: 8-12


	© Nilanjan Roy Ph.D. last updated Jan, 2006